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Pore Structure and Synergy in Antimicrobial Peptides of the Magainin Family.

Magainin 2 and PGLa are among the best-studied cationic antimicrobial peptides. They bind preferentially to negatively charged membranes and apparently cause their disruption by the formation of transmembrane pores, whose detailed structure is still unclear. Here we report the results of 5-9 μs all-...

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Autori principali: Almudena Pino-Angeles, John M Leveritt, Themis Lazaridis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2016-01-01
Serie:PLoS Computational Biology
Accesso online:http://europepmc.org/articles/PMC4699650?pdf=render
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