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Testing if Micro-CT Is Capable of Quantitating the Extent of Proteoglycan-Aggrecan Induced Axial Spondyloarthritis in Mice

ObjectiveInjections of proteoglycan aggrecan (PGA) have been reported to induce axial spondyloarthritis (ax-SpA) in BALB/c mice. It is considered to be a model for radiographic ax-SpA. However, evaluation of the extent of axial disease by histopathological assessment of every intervertebral space is...

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Principais autores: Qing Han, ZhaoHui Zheng, Qiang Liang, Kui Zhang, FengFan Yang, XiangHui Fu, Xing Luo, Jin Ding, Ronghua Xie, WenXiao Zhu, Ping Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-07-01
coleção:Frontiers in Immunology
Assuntos:
spondyloarthritis
proteoglycan
aggrecan
BALB/c
animal models
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2021.681217/full
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