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Glycosylation of TRPM4 and TRPM5 channels: molecular determinants and functional aspects

The transient receptor potential channel, TRPM4, and its closest homologue, TRPM5, are non-selective cation channels that are activated by an increase in intracellular calcium. They are expressed in many cell types, including neurons and myocytes. Although the electrophysiological and pharmacologica...

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Principais autores: Ninda eSyam, Jean-Sebastien eRougier, Hugues eAbriel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014-02-01
coleção:Frontiers in Cellular Neuroscience
Assuntos:
Ion Channels
regulation
Trpm5
TRPM4
N-linked glycosylation
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fncel.2014.00052/full
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