Genome agnostic, multi-level non-oncogene addiction-based systems pharmacology for rescuing metastatic relapsed/refractory neoplasias

Rescue therapies for relapsed/refractory (r/r) metastatic neoplasias present significant unmet needs. Tumor tissue editing regimen for 13 r/r tumor types, carcinomas, sarcomas and hematologic neoplasias, included in 15 phase I/II trials, nuclear/cytokine receptor agonists, pioglitazone, plus/minus d...

Description complète

Détails bibliographiques

Auteurs principaux:	Dennis Christoph Harrer, Florian Lüke, Tobias Pukrop, Lina Ghibelli, Albrecht Reichle, Daniel Heudobler
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-02-01
Collection:	Frontiers in Pharmacology
Sujets:	acute myelocytic leukemia all-trans retinoic acid anakoinosis angiosarcoma azacitidine cancer hallmarks
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1629187/full
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!