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Nanoscopic Spatial Association between Ras and Phosphatidylserine on the Cell Membrane Studied with Multicolor Super Resolution Microscopy

Recent work suggests that Ras small GTPases interact with the anionic lipid phosphatidylserine (PS) in an isoform-specific manner, with direct implications for their biological functions. Studies on PS-Ras associations in cells, however, have relied on immuno-EM imaging of membrane sheets. To study...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Anna M. Koester, Kai Tao, Malwina Szczepaniak, Matthew J. Rames, Xiaolin Nan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-07-01
Schriftenreihe:Biomolecules
Schlagworte:
Ras GTPases
membrane nanodomains
nanoclusters
Ras dimers
phosphatidylserine
super resolution microscopy
Online-Zugang:https://www.mdpi.com/2218-273X/12/8/1033
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