Integrating advanced analytical methods to assess epigenetic marks affecting response to hypomethylating agents in higher risk myelodysplastic syndrome

Abstract Background Patients with higher-risk (HR) myelodysplastic syndrome (MDS), ineligible for allogeneic hematopoietic stem cell transplantation (alloHSCT), require prompt therapeutic interventions, such as treatment with hypomethylating agents (HMAs) to restore normal DNA methylation patterns,...

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主要な著者:	Theodoros Nikolopoulos, Eleftherios Bochalis, Theodora Chatzilygeroudi, Vasiliki Chondrou, Irene Dereki, Katerina Athanasopoulou, John Zafeiropoulos, Kyriakos Bourikas, George P. Patrinos, Argiris Symeonidis, Argyro Sgourou
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-02-01
シリーズ:	Molecular Medicine
主題:	Myelodysplastic syndromes Hypomethylating agents Response assessment DNA methylation LC-MS/MS analysis MeD-seq data analysis
オンライン･アクセス:	https://doi.org/10.1186/s10020-025-01123-7
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