Potent antitumor efficacy of human dental pulp stem cells armed with YSCH-01 oncolytic adenovirus

Abstract Background Systemic administration of oncolytic adenovirus for cancer therapy is still a challenge. Mesenchymal stem cells as cell carriers have gained increasing attention in drug delivery due to their excellent tumor tropism, immunosuppressive modulatory effects, and paracrine effects. Ho...

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Autori principali:	Xu He, Wei Yao, Ji-Ding Zhu, Xin Jin, Xin-Yuan Liu, Kang-Jian Zhang, Shou-Liang Zhao
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-10-01
Serie:	Journal of Translational Medicine
Soggetti:	Human dental pulp stem cell Oncolytic adenovirus Cell carrier Tumor tropism Intraperitoneal injection Cancer therapy
Accesso online:	https://doi.org/10.1186/s12967-023-04539-z
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