Insight in HIV Integration Site Selection Provides a Block-and-Lock Strategy for a Functional Cure of HIV Infection

Despite significant improvements in therapy, the HIV/AIDS pandemic remains an important threat to public health. Current treatments fail to eradicate HIV as proviral DNA persists in long-living cellular reservoirs, leading to viral rebound whenever treatment is discontinued. Hence, a better understa...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Zeger Debyser, Gerlinde Vansant, Anne Bruggemans, Julie Janssens, Frauke Christ
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2018-12-01
Цуврал:	Viruses
Нөхцлүүд:	human immunodeficiency virus integrase integration site selection LEDGF/p75 HRP-2 LEDGIN block-and-lock HIV cure
Онлайн хандалт:	http://www.mdpi.com/1999-4915/11/1/12
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!