Circulating IL-33 as a sensitive alarmin in systemic lupus erythematosus: a biomarker for disease activity and skin-specific manifestations

Abstract Interleukin-33 (IL-33), an alarmin predominantly released by keratinocytes and endothelial cells, plays a pivotal role in type 2 immune responses and has been linked to the pathogenesis of autoimmune diseases, including systemic lupus erythematosus (SLE). This study aimed to explore the rel...

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Hlavní autoři:	Li Li, Xi Tan, Chen Zhao, Sijian Wen, Wenyu Li, Runge Fan, Wei Hou, Youkun Lin
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-05-01
Edice:	Scientific Reports
Témata:	Systemic lupus erythematosus IL-33 Photosensitivity Biomarker
On-line přístup:	https://doi.org/10.1038/s41598-026-48284-x
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