Identification of PADI2 as a potential breast cancer biomarker and therapeutic target

<p>Abstract</p> <p>Background</p> <p>We have recently reported that the expression of peptidylarginine deiminase 2 (PADI2) is regulated by EGF in mammary cancer cells and appears to play a role in the proliferation of normal mammary epithelium; however, the role of PADI2 in the pathogenesis of human...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	McElwee John L, Mohanan Sunish, Griffith Obi L, Breuer Heike C, Anguish Lynne J, Cherrington Brian D, Palmer Ashley M, Howe Louise R, Subramanian Venkataraman, Causey Corey P, Thompson Paul R, Gray Joe W, Coonrod Scott A
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2012-10-01
Σειρά:	BMC Cancer
Θέματα:	Peptidylarginine deiminase PAD2/PADI2 HER2/ERBB2 Breast cancer Luminal Cl-amidine Citrullination
Διαθέσιμο Online:	http://www.biomedcentral.com/1471-2407/12/500
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