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Developmental epigenetic programming by Tet1/3 determines peripheral CD8 T cell fate

Abstract In response to infections, naive CD8 T cells give rise to effector and memory T cells. However, eliciting long-lived memory CD8 T cells remains a challenge for many infections. DNA demethylation of cytosines within CpG dinucleotides by Tet enzymes is a key epigenetic mechanism that regulate...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Kara M Misel-Wuchter, Andrew L Thurman, Jordan T Johnson, Athmane Teghanemt, Neelam Gautam, Alejandro A Pezzulo, Jennifer R Bermick, Noah S Butler, Priya D Issuree
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Springer Nature 2025-04-01
Rangatū:EMBO Reports
Ngā marau:
Urunga tuihono:https://doi.org/10.1038/s44319-025-00439-z
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