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PHILADELPHIA CHROMOSOME-NEGATIVE CHRONIC MYELOID LEUKEMIA WITH BCR::ABL1 FUSION

Introduction: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the chromosome philadelphia (Ph) in 90-95% of cases. The Ph chromosome results from the reciprocal t(9;22)(q34.1;q11.2) and encodes the fusion gene BCR::ABL1. The chimeric tyrosine kinase oncoprotein is co...

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Principais autores: MCS Sousa, L Otero, AF Monteiro, NC Amaral, MM Rocha, ILS Pinto, I Zalcberg, BCR Monte-Mór, LM Gutiyama
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-10-01
Serier:Hematology, Transfusion and Cell Therapy
Online adgang:http://www.sciencedirect.com/science/article/pii/S2531137924011659
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