Evolution from XIST-independent to XIST-controlled X-chromosome inactivation: epigenetic modifications in distantly related mammals.

X chromosome inactivation (XCI) is the transcriptional silencing of one X in female mammals, balancing expression of X genes between females (XX) and males (XY). In placental mammals non-coding XIST RNA triggers silencing of one X (Xi) and recruits a characteristic suite of epigenetic modifications,...

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Detalhes bibliográficos

Principais autores:	Julie Chaumeil, Paul D Waters, Edda Koina, Clément Gilbert, Terence J Robinson, Jennifer A Marshall Graves
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2011-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3081832?pdf=render
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