Upper and Lower Motor Neuron Degenerations Are Somatotopically Related and Temporally Ordered in the <i>Sod1</i> Mouse Model of Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a devastating and fatal neurodegenerative disease arising from the combined degeneration of upper motor neurons (UMN) in the motor cortex, and lower motor neurons (LMN) in the brainstem and spinal cord. This dual impairment raises two major questions: (i) are t...

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Hlavní autoři:	Christine Marques, Thibaut Burg, Jelena Scekic-Zahirovic, Mathieu Fischer, Caroline Rouaux
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-03-01
Edice:	Brain Sciences
Témata:	amyotrophic lateral sclerosis motor cortex upper motor neurons lower motor neurons somatotopy descending propagation
On-line přístup:	https://www.mdpi.com/2076-3425/11/3/369
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