Exploiting similarity in drug molecular effects for drug repurposing

Abstract Background Using large data to propose new uses of drugs has potential to rapidly prioritize new treatments for major diseases of public health importance. One comprehensive data set, LINCS L1000 Connectivity Map, profiles gene expression associated with thousands of compounds, including ma...

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Principais autores:	Katie Huang, Panagiotis Nikolaos Lalagkas, Beftu Sultan, Rachel Melamed
格式:	Artigo
語言:	Inglês
出版:	BMC 2025-09-01
叢編:	Human Genomics
主題:	Drug repositioning Gene expression Drug discovery
在線閱讀:	https://doi.org/10.1186/s40246-025-00808-8
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