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Mechanistic aspects of maltotriose-conjugate translocation to the Gram-negative bacteria cytoplasm

A maltotriose-conjugate can deliver molecules into the cytoplasmic space of Gram-negative bacteria by parasitizing the maltose uptake pathway. Small molecule accumulation in Gram-negative bacteria is a key challenge to discover novel antibiotics, because of their two membranes and efflux pumps expel...

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Detalhes bibliográficos
Principais autores: Estelle Dumont, Julia Vergalli, Jelena Pajovic, Satya P Bhamidimarri, Koldo Morante, Jiajun Wang, Dmitrijs Lubriks, Edgars Suna, Robert A Stavenger, Mathias Winterhalter, Matthieu Réfrégiers, Jean-Marie Pagès
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2019-02-01
coleção:Life Science Alliance
Acesso em linha:https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.201800242
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