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LncRNA Dlx4os drives malignant transformation and phenotype switching in melanoma

Cutaneous melanoma, a highly aggressive and therapy-resistant skin cancer, is characterized by its remarkable cellular plasticity, enabling tumour cells to switch between different phenotypic states. This plasticity contributes to tumour heterogeneity and is regulated by key transcription factors. L...

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Principais autores: Ana Luisa Pedroso Ayub, Beatriz Cristina Biz Tonin, Hátylas Azevedo, Pedro Henrique Fogaça Jordão, Tanvi Saxena, Leinal Sejour, Jeremie Nsengimana, Ioannis Vlachos, Eduardo Moraes Reis, Frank John Slack, Miriam Galvonas Jasiulionis
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2026-12-01
coleção:Epigenetics
Assuntos:
Melanoma
lncRNAs
plasticity
phenotype switching
malignant transformation
Acesso em linha:https://www.tandfonline.com/doi/10.1080/15592294.2026.2641924
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