Resolving the renal microenvironment: a 5-plex immunofluorescence workflow to quantify B-lineage cells in FFPE lupus nephritis biopsies

Accurate identification and spatial enumeration of B lineage cells in formalin-fixed, paraffin-embedded (FFPE) lupus nephritis (LN) kidney tissue is critical for understanding disease pathogenesis and CD20-directed therapeutic responses. We developed a targeted 5-plex immunofluorescence and digital...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Caleb Chan, Patrick S. Chang, Sreedevi Chalasani, Janet Tao, Harini Raghu, Cary D. Austin
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2026-03-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	antibody-secreting cells ASCs B cells FFPE immunofluorescence lupus nephritis
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1774536/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!