Clinical study of PLA2R epitope spreading for predicting proteinuria remission in primary membranous nephropathy

IntroductionM-type phospholipase A2 receptor (PLA2R) is the predominant autoantigen in primary membranous nephropathy (PMN), accounting for approximately 70%–80% of cases. Circulating anti-PLA2R IgG is a widely used biomarker to monitor disease activity and treatment. In recent years, antibodies tar...

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Detalhes bibliográficos

Principais autores:	Xueyang Cheng, Meiyi Zhou, Caimei Chen, Jing Xue, Bin Liu, Zhijian Zhang, Xiran Zhang, Leting Zhou, Ting Cai, Biao Huang, Yi Zhang, Liang Wang, Xiaobin Liu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-10-01
coleção:	Frontiers in Immunology
Assuntos:	primary membranous nephropathy PLA2R epitope spreading rituximab anti-rituximab antibody
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1685738/full
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