In vitro efficacy of ceftazidime/avibactam and cefiderocol against multidrug-resistant Gram-negative uropathogens: insights into β-lactamase-mediated resistance in clinical isolates

Abstract Background Urinary tract infections (UTIs) are among the most common bacterial infections in hospitalized patients, frequently caused by Gram-negative bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Pseudomonas aeruginosa. The increasing prevalence of multid...

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Autores principales:	Mohamed A. Ibrahim, Hisham A. Abbas, Ghada H. Shaker, Ahmed M. El-Baz
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	SpringerOpen 2026-04-01
Colección:	Future Journal of Pharmaceutical Sciences
Materias:	β-lactamases Cefiderocol Ceftazidime/avibactam Gram-negative bacteria Multidrug resistant Urinary tract infections
Acceso en línea:	https://doi.org/10.1186/s43094-026-00946-3
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