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LncRNA XIST promoted the stability of TLR9 mRNA in a FUS-dependent manner to facilitate aerobic glycolysis and proliferation in Th17/CD4+T cells

ObjectiveTo explore the expression and function of lncRNA XIST in Th17 cells in IgA nephropathy (IgAN) and examine the regulation of lncRNA XIST on TLR9 mRNA expression.MethodsCD4+T cells were isolated from peripheral blood mononuclear cells (PBMCs) and induced to differentiate into Th17 cells.XIST...

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Autors principals: Wu Yan-ping, Ma Xiao, Han Si-ping, Wang Xiao-qin
Format: Artigo
Idioma:Chinês
Publicat: Editorial Department of Journal of Clinical Nephrology 2022-05-01
Col·lecció:Linchuang shenzangbing zazhi
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Accés en línia:http://www.lcszb.com/thesisDetails#10.3969/j.issn.1671-2390.2022.05.008
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