Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases

Abstract Cytochrome bd-type oxidases play a crucial role for survival of pathogenic bacteria during infection and proliferation. This role and the fact that there are no homologues in the mitochondrial respiratory chain qualify cytochrome bd as a potential antimicrobial target. However, few bd oxida...

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Detalhes bibliográficos

Principais autores:	Melanie Radloff, Isam Elamri, Tamara N. Grund, Luca F. Witte, Katharina F. Hohmann, Sayaka Nakagaki, Hojjat G. Goojani, Hamid Nasiri, Hideto Miyoshi, Dirk Bald, Hao Xie, Junshi Sakamoto, Harald Schwalbe, Schara Safarian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2021-12-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-021-03288-7
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