Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
Abstract Due to a demonstrated lack of DNA repair deficiencies, clear cell renal cell carcinoma (ccRCC) has not benefitted from targeted synthetic lethality-based therapies. We investigated whether nucleotide excision repair (NER) deficiency is present in an identifiable subset of ccRCC cases that w...
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| Główni autorzy: | , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2023-11-01
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| Seria: | Scientific Reports |
| Dostęp online: | https://doi.org/10.1038/s41598-023-47946-4 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
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