Obesity induces phenotypic switching of gastric smooth muscle cells through the activation of the PPARD/PDK4/ANGPTL4 pathway

Abstract Background Clinical research has identified stomach dysmotility as a common feature of obesity. However, the specific mechanisms driving gastric emptying dysfunction in patients with obesity remain largely unknown. In this study, we investigated potential mechanisms by focusing on the homeo...

Descripció completa

Dades bibliogràfiques

Autors principals:	Sanaa Dekkar, Kamilia Mahloul, Amandine Falco, Karidia Konate, Romane Pisteur, Sarah Maurel, Laurent Maïmoun, Norbert Chauvet, Prisca Boisguérin, David Nocca, Ariane Sultan, Florian Pallot, Guillaume Walther, Nicolas Cenac, Cyril Breuker, Sandrine Faure, Pascal de Santa Barbara
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-07-01
Col·lecció:	Journal of Biomedical Science
Matèries:	Smooth muscle Obesity Stomach Immaturity PDK4/ANGPTL4/PPARD pathway
Accés en línia:	https://doi.org/10.1186/s12929-025-01163-5
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!