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Monoterpene Indole Alkaloids from the Aerial Parts of <i>Rhazya stricta</i> Induce Cytotoxicity and Apoptosis in Human Adenocarcinoma Cells

Chromatographic investigation of the aerial parts of the <i>Rhazya stricta</i> (Apocynaceae) resulted in the isolation of two new monoterpene indole alkaloids, 6-<i>nor</i>-antirhine-<i>N<sub>1</sub></i>-methyl (<b>1</b>) and razyamide (<b>2</b>), along with six known compounds, eburenine (<b>3</b>)...

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Main Authors: Zainab H. Abdul-Hameed, Nahed O. Bawakid, Hajer S. Alorfi, Tariq R. Sobahi, Najla Ali Alburae, Ahmed Abdel-Lateff, Serag Eldin I. Elbehairi, Mohammad Y. Alfaifi, Nabil A. Alhakamy, Walied M. Alarif
Format: Artigo
Language:Inglês
Published: MDPI AG 2022-02-01
Series:Molecules
Subjects:
Saudi plants
Apocynaceae
alkaloids
cytotoxicity
MCF-7
HepG2
Online Access:https://www.mdpi.com/1420-3049/27/4/1422
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