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Discovery of Inhibitors of Insulin-Regulated Aminopeptidase as Cognitive Enhancers

The hexapeptide angiotensin IV (Ang IV) is a metabolite of angiotensin II (Ang II) and plays a central role in the brain. It was reported more than two decades ago that intracerebroventricular injection of Ang IV improved memory and learning in the rat. Several hypotheses have been put forward to ex...

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Bibliografiske detaljer
Principais autores: Hanna Andersson, Mathias Hallberg
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2012-01-01
Serier:International Journal of Hypertension
Online adgang:http://dx.doi.org/10.1155/2012/789671
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