Differential scanning calorimetric study of antibiotic distamycin A binding with chromatin within isolated rat liver nuclei

Context: Natural oligopeptide antibiotic distamycin A (Dst) biosynthesized by Streptomyces distallicus is traditionally used in medical practice as an anti-inflammatory and antitumour drug. Objective: Dst was investigated for its effect on the structural components of native chromatin directly withi...

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Hauptverfasser:	Andrey N. Prusov, Galina Ya. Kolomijtseva, Tatiana A. Smirnova
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2017-01-01
Schriftenreihe:	Pharmaceutical Biology
Schlagworte:	nuclei chromatin structure differential scanning calorimetry distamycin a
Online-Zugang:	http://dx.doi.org/10.1080/13880209.2016.1258427
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