FBXL17/spastin axis as a novel therapeutic target of hereditary spastic paraplegia
Abstract Background Spastin significantly influences microtubule regulation in neurons and is implicated in the pathogenesis of hereditary spastic paraplegia (HSP). However, post-translational regulation of the spastin protein remains nebulous. The association between E3 ubiquitin ligase and spastin...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2022-07-01
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| Serier: | Cell & Bioscience |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s13578-022-00851-1 |
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