Retinoic acid-induced CYP51 nuclear translocation promotes meiosis prophase I process and is correlated to the expression of REC8 and STAG3 in mice

Lanosterol 14 α-demethylase (CYP51) plays a crucial role in cholesterol biosynthesis. In gamete development, CYP51 is involved in initiating meiosis resumption in oocytes through its product, meiosis activating sterol (MAS). In this study, CYP51 was observed to localize within the nucleus of germ ce...

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主要な著者:	Xinyi Mu, Jia Wen, Qian Chen, Zhengpin Wang, Yijing Wang, Meng Guo, Yi Yang, JinRui Xu, Zhiqing Wei, Guoliang Xia, Mengye Yang, Chao Wang
フォーマット:	Artigo
言語:	Inglês
出版事項:	The Company of Biologists 2018-11-01
シリーズ:	Biology Open
主題:	CYP51 Oocytes Meiosis Chromosome synapsis Primordial follicle formation
オンライン･アクセス:	http://bio.biologists.org/content/7/11/bio035626
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