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Autophagy and autophagic cell death in sepsis: friend or foe?

Abstract In sepsis, inflammation, and nutrient deficiencies endanger cellular homeostasis and survival. Autophagy is primarily a mechanism of cellular survival under fasting conditions. However, autophagy-dependent cell death, known as autophagic cell death, is proinflammatory and can exacerbate sep...

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Bibliografische Detailangaben
Hauptverfasser: Toshiaki Iba, Julie Helms, Cheryl L. Maier, Ricard Ferrer, Jerrold H. Levy
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-10-01
Schriftenreihe:Journal of Intensive Care
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Online-Zugang:https://doi.org/10.1186/s40560-024-00754-y
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