Spermidine Inhibits M1 Microglia Polarization in a Mouse Model of Parkinson's Disease and BV2 Cells via NF‐κB/STAT‐1 Pathway

ABSTRACT Background Excessively activated M1 microglia release proinflammatory factors that can cause neuronal death and contribute to the development of Parkinson's disease (PD). Recent research indicates that spermidine, a naturally occurring polyamine, may have anti‐inflammatory properties. Nonet...

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Главные авторы:	Jun Shu, Yuqiong Jiao, Wenshi Wei, Aijuan Yan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Wiley 2025-03-01
Серии:	Brain and Behavior
Предметы:	microglial polarization neuroinflammation Parkinson's disease spermidine
Online-ссылка:	https://doi.org/10.1002/brb3.70410
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