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MDM2 regulates the stability of AR, AR-V7, and TM4SF3 proteins in prostate cancer

Androgen receptor (AR) and its constitutively active splice variant, AR Variant 7 (AR-V7), regulate genes essential for the development and progression of prostate cancer. Degradation of AR and AR-V7 by the ubiquitination proteasomal pathway is important for the regulation of both their protein stab...

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Principais autores: Prabesh Khatiwada, Ujjwal Rimal, Zhengyang Han, Lirim Shemshedini
Formato: Artigo
Idioma:Inglês
Publicado: Bioscientifica 2024-02-01
Series:Endocrine Oncology
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Acceso en liña:https://eo.bioscientifica.com/view/journals/eo/4/1/EO-23-0017.xml
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