Genomic landscape of clinically advanced KRAS wild-type pancreatic ductal adenocarcinoma

IntroductionKRAS mutation is a common occurrence in Pancreatic Ductal Adenocarcinoma (PDA) and is a driver mutation for disease development and progression. KRAS wild-type PDA may constitute a distinct molecular and clinical subtype. We used the Foundation one data to analyze the difference in Genom...

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Hlavní autoři:	Prashanth Ashok Kumar, Serenella Serinelli, Daniel J. Zaccarini, Richard Huang, Natalie Danziger, Tyler Janovitz, Alina Basnet, Abirami Sivapiragasam, Stephen Graziano, Jeffrey S. Ross
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-06-01
Edice:	Frontiers in Oncology
Témata:	pancreatic ductal adenocarcinoma KRAS mutation KRAS wild-type pancreatic cancer genomic alterations targeted therapy
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1169586/full
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