Unveiling the Role of Cholesterol in Subnanomolar Ouabain Rescue of Cortical Neurons from Calcium Overload Caused by Excitotoxic Insults

Na/K-ATPase maintains transmembrane ionic gradients and acts as a signal transducer when bound to endogenous cardiotonic steroids. At subnanomolar concentrations, ouabain induces neuroprotection against calcium overload and apoptosis of neurons during excitotoxic stress. Here, the role of lipid raft...

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Главные авторы:	Dmitry A. Sibarov, Zoia D. Zhuravleva, Margarita A. Ilina, Sergei I. Boikov, Yulia D. Stepanenko, Tatiana V. Karelina, Sergei M. Antonov
Формат:	Artigo
Язык:	Inglês
Опубликовано:	MDPI AG 2023-08-01
Серии:	Cells
Предметы:	NMDA receptor neurons Na/K-ATPase cholesterol calcium Na/Ca exchanger
Online-ссылка:	https://www.mdpi.com/2073-4409/12/15/2011
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