Tumor-derived exosomal circFARSA mediates M2 macrophage polarization via the PTEN/PI3K/AKT pathway to promote non-small cell lung cancer metastasis

Background: Exosomes in the tumor microenvironment (TME) facilitate tumor progression by enabling inter-cellular communication. Tumor cell-derived exosomes can polarize tumor-associated macrophages (TAMs) to an immunosuppressive M2 phenotype. The aim of this study was to determine the role of exosom...

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Auteurs principaux:	Tengfei Chen, Yali Liu, Chang Li, Chun Xu, Cheng Ding, Jun Chen, Jun Zhao
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2021-01-01
Collection:	Cancer Treatment and Research Communications
Sujets:	Exosomes Macrophages CircFARSA NSCLC Metastasis
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S2468294221001106
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