Initiation of SGLT2 inhibitors versus mineralocorticoid receptor antagonists as third-line therapy in heart failure with reduced ejection fraction: a nationwide cohort studyResearch in context

Summary: Background: Heart failure with reduced ejection fraction (HFrEF) guidelines recommend early initiation of four foundational therapies—renin-angiotensin system inhibitors (RASI), beta-blockers, mineralocorticoid receptor antagonists (MRAs), and sodium-glucose co-transporter 2 (SGLT2) inhibi...

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Bibliografische gegevens

Hoofdauteurs:	Henrik Svanström, George Frederick Mkoma, Anders Hviid, Björn Pasternak
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2026-01-01
Reeks:	The Lancet Regional Health. Europe
Onderwerpen:	Heart failure with reduced ejection fraction Sodium-glucose cotransporter 2 inhibitors Mineralocorticoid receptor antagonists Comparative effectiveness Treatment sequencing Real-world evidence
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2666776225003023
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