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Third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiency

Summary: Rabies viral vectors have become important components of the systems neuroscience toolkit, allowing both direct retrograde targeting of projection neurons and monosynaptic tracing of inputs to defined postsynaptic populations, but the rapid cytotoxicity of first-generation (ΔG) vectors limi...

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Autori principali: Lei Jin, Heather A. Sullivan, Mulangma Zhu, Nicholas E. Lea, Thomas K. Lavin, Xin Fu, Makoto Matsuyama, YuanYuan Hou, Guoping Feng, Ian R. Wickersham
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2023-11-01
Serie:Cell Reports: Methods
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Accesso online:http://www.sciencedirect.com/science/article/pii/S2667237523003156
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