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Mutational profile of oropharyngeal squamous cell carcinoma in relation to HPV, tobacco smoking and prognosis with validation in the DAHANCA 19 randomized trial

Background and purpose: This study investigated prognostic biomarkers in oropharyngeal squamous cell carcinoma (OPSCC), with a focus on tumors related to human papillomavirus (HPV) infection and potential molecular effects of tobacco smoking, as smokers with HPV+ OPSCC often have poorer outcomes. P...

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Autors principals: Jacob Lilja-Fischer, Morten Horsholt Kristensen, Pernille Lassen, Torben Steiniche, Trine Tramm, Magnus Stougaard, Anders Frederiksen, Benedicte Ulhøi, Jan Alsner, Kasper Toustrup, Christian Maare, Jørgen Johansen, Hanne Primdahl, Claus Andrup Kristensen, Maria Andersen, Jesper Grau Eriksen, Jens Overgaard
Format: Artigo
Idioma:Inglês
Publicat: Medical Journals Sweden 2025-08-01
Col·lecció:Acta Oncologica
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Accés en línia:https://medicaljournalssweden.se/actaoncologica/article/view/44042
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