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Platelet-rich plasma respectively reduces and promotes adipogenic and myofibroblastic differentiation of human adipose-derived stromal cells via the TGFβ signalling pathway

Abstract Autologous fat grafting is a gold standard therapy for soft tissue defects, but is hampered by unpredictable postoperative outcomes. Fat graft enrichment with adipose-derived stromal cell (ASCs) was recently reported to enhance graft survival. Platelet-rich plasma (PRP) has also emerged as...

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Detalhes bibliográficos
Principais autores: Bérengère Chignon-Sicard, Magali Kouidhi, Xi Yao, Audrey Delerue-Audegond, Phi Villageois, Pascal Peraldi, Patricia Ferrari, Yves Rival, David Piwnica, Jérôme Aubert, Christian Dani
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2017-06-01
coleção:Scientific Reports
Acesso em linha:https://doi.org/10.1038/s41598-017-03113-0
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