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Tertiary lymphoid structures in high-grade serous tubo-ovarian carcinoma: anatomical site matters

Abstract Tertiary lymphoid structures (TLS) in the tumor microenvironment are prognostically beneficial in many solid cancer types. Reports on TLS in high-grade serous tubo-ovarian carcinoma (HGSC) are few, and the prognostic impact is unclear. We investigated mature TLS (mTLS), immature TLS (iTLS)...

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Principais autores: Sofia Westbom-Fremer, Lena Tran, Anna Ebbesson, Laura Martin de la Fuente, Jenny-Maria Jönsson, Päivi Kannisto, Srinivas Veerla, Ingrid Hedenfalk
Format: Artigo
Sprog:Inglês
Udgivet: Springer 2025-01-01
Serier:Cancer Immunology, Immunotherapy
Fag:
Tertiary lymphoid structure
High-grade serous carcinoma
Metastasis
Prognosis
Online adgang:https://doi.org/10.1007/s00262-024-03911-2
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