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Design, Immunogenicity and Preclinical Efficacy of the ChAdOx1.COVconsv12 Pan-Sarbecovirus T-Cell Vaccine

During the COVID-19 pandemic, antibody-based vaccines targeting the SARS-CoV-2 spike glycoprotein were the focus for development because neutralizing antibodies were associated with protection against the SARS-CoV-2 infection pre-clinically and in humans. While deploying these spike-based vaccines s...

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Principais autores: Edmund G.-T. Wee, Sarah Kempster, Deborah Ferguson, Joanna Hall, Claire Ham, Susan Morris, Alison Crook, Sarah C. Gilbert, Bette Korber, Neil Almond, Tomáš Hanke
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-08-01
Serier:Vaccines
Fag:
COVID-19 vaccine
T cells
T cell vaccine
COVID-19 T cells
ChAdOx1
conserved region
Online adgang:https://www.mdpi.com/2076-393X/12/9/965
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