The role of alkyl chain length in the melt and solution crystallization of paliperidone aliphatic prodrugs

Fatty acid-derivative prodrugs have been utilized extensively to improve the physicochemical, biopharmaceutical and pharmacokinetic properties of active pharmaceutical ingredients. However, to our knowledge, the crystallization behavior of prodrugs modified with different fatty acids has not been ex...

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Manylion Llyfryddiaeth

Prif Awduron:	An Chen, Peishan Cai, Yayun Peng, Minshan Guo, Yuan Su, Ting Cai
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	International Union of Crystallography 2024-01-01
Cyfres:	IUCrJ
Pynciau:	paliperidone prodrugs alkyl chain lengths crystallization kinetics crystal engineering crystal morphology intermolecular interactions pharmaceutical solids
Mynediad Ar-lein:	http://scripts.iucr.org/cgi-bin/paper?S2052252523009582
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