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Differential CD4+ T-Cell Cytokine and Cytotoxic Responses Between Reactivation and Latent Phases of Herpes Zoster Infection

Background: CD4+ T cells are a critical component of effective immune responses to varicella zoster virus (VZV), but their functional properties during the reactivation acute vs latent phase of infection remain poorly defined. Methods: Here we assessed the functional and transcriptomic properties...

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Autori principali: Wenjie Jin, Mike Fang, Ismail Sayin, Carson Smith, Jeffrey Hunter, Brian Richardson, Jackelyn Golden, Christopher Haley, Kenneth Schmader, Michael Betts, Cheryl Cameron, Stephen Tyring, Mark Cameron, David Canaday
Natura: Artigo
Lingua:Inglês
Pubblicazione: Case Western Reserve University 2023-02-01
Serie:Pathogens and Immunity
Soggetti:
VZV;
Herpes Zoster;
T-cell polyfunction;
CD4 T cells;
transcriptomic
Accesso online:https://www.paijournal.com/index.php/paijournal/article/view/560
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