A refined TTC assay precisely detects cardiac injury and cellular viability in the infarcted mouse heart

Abstract Histological analysis with 2,3,5-triphenyltetrazolium chloride (TTC) staining is the most frequently used tool to detect myocardial ischemia/reperfusion injury. However, its practicality is often challenged by poor image quality in gross histology, leading to an equivocal infarct-boundary d...

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Detalles Bibliográficos

Principais autores:	Zheheng Ding, Xueqing Liu, Hongyan Jiang, Jianfeng Zhao, Sebastian Temme, Pascal Bouvain, Christina Alter, Puyan Rafii, Jürgen Scheller, Ulrich Flögel, Hongtao Zhu, Zhaoping Ding
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2024-10-01
Series:	Scientific Reports
Assuntos:	Area-at-risk (AAR) Cardioprotection CBB redTTC Myocardial infarction Myocardial infarct size (mIS)
Acceso en liña:	https://doi.org/10.1038/s41598-024-76414-w
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