Suppressed HIV antibody responses following exposure to antiretrovirals—evidence from PrEP randomized trials and early antiretroviral treatment initiation studies

Background: Exposure to antiretrovirals at or early after HIV acquisition can suppress viral replication and blunt antibody (Ab) responses; a reduced HIV detectability could impact diagnosis and blood donation screening. Methods: We used three antigen (Ag)/Ab assays and one nucleic acid test (NAT) t...

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Автори:	Vivian I. Avelino-Silva, Mars Stone, Sonia Bakkour, Clara Di Germanio, Michael Schmidt, Ashtyn L. Conway, David Wright, Eduard Grebe, Brian Custer, Steven H. Kleinman, Xutao Deng, Jairam R. Lingappa, Patricia Defechereux, Megha Mehrotra, Robert M. Grant, Sandhya Vasan, Shelley Facente, Nittaya Phanuphak, Carlo Sacdalan, Siriwat Akapirat, Mark de Souza, Michael P. Busch, Philip J. Norris
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2024-11-01
Серія:	International Journal of Infectious Diseases
Предмети:	HIV testing Serologic tests Antiretroviral therapy Pre-exposure prophylaxis Diagnostics Delayed diagnosis
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S1201971224002935
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