Current status and perspectives of hematopoietic cell transplantation in patients with paroxysmal nocturnal hemoglobinuria

BackgroundParoxysmal nocturnal hemoglobinuria (PNH) is a rare complement-driven acquired hemolytic anemia with specific presentations of hemoglobinuria, abdominal pain, fatigue, and thrombosis.ObjectiveTo review the current therapeutic strategies for PNH, including anti-complement therapy and alloge...

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Autores principales:	Marek Ussowicz, Dawid Przystupski, Patrycja Mensah-Glanowska, Agnieszka Piekarska
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2025-01-01
Colección:	Frontiers in Immunology
Materias:	PNH aplastic anemia hematopoietic cell transplantation paroxysmal nocturnal hemoglobinuria conditioning
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1521484/full
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