Parallel in vitro ion channel and in vivo zebrafish assaying of elapid snake venoms following chromatographic separation of toxin components

Snake venoms are complex bioactive mixtures designed to paralyse, kill, or digest prey. These venoms are of pharmacological interest due to their ability to modulate molecular targets such as ion channels and receptors with high specificity and potency. Traditional studies often focus on in vitro mo...

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Autors principals:	Arif Arrahman, Haifeng Xu, Muzaffar A. Khan, Tijmen S. Bos, Julien Slagboom, Guus C. van der Velden, Ulrike Nehrdich, Nicholas R. Casewell, Michael K. Richardson, Christian Tudorache, Fernanda C. Cardoso, Jeroen Kool
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2025-07-01
Col·lecció:	SLAS Discovery
Matèries:	Elapid snake venom zebrafish in vivo assay ion channel in vitro assays mass spectrometry nanofractionation toxicity assay
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S2472555225000322
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