Metabolomics integrated genomics approach: Understanding multidrug resistance phenotype in MCF-7 breast cancer cells exposed to doxorubicin and ABCA1/EGFR/PI3k/PTEN crosstalk

Resistance of cancer cells, especially breast cancer, to therapeutic medicines represents a major clinical obstacle that impedes the stages of treatment. Carcinoma cells that acquire resistance to therapeutic drugs can reprogram their own metabolic processes as a way to overcome the effectiveness of...

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Asıl Yazarlar:	Mai O. Kadry, Gamal Eldein Fathy Abd-Ellatef, Naglaa M. Ammar, Heba A. Hassan, Noha S. Hussein, Nahla N. Kamel, Maha M. Soltan, Rehab M. Abdel-Megeed, Abdel-Hamid Z. Abdel-Hamid
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Elsevier 2025-06-01
Seri Bilgileri:	Toxicology Reports
Konular:	Breast cancer ABCA1 Metabolomics EGFR PTEN
Online Erişim:	http://www.sciencedirect.com/science/article/pii/S2214750024002701
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