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The Inflammatory Profile of CTEPH-Derived Endothelial Cells Is a Possible Driver of Disease Progression

Chronic thromboembolic pulmonary hypertension (CTEPH) is a form of pulmonary hypertension characterized by the presence of fibrotic intraluminal thrombi and causing obliteration of the pulmonary arteries. Although both endothelial cell (EC) dysfunction and inflammation are linked to CTEPH pathogenes...

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Principais autores: Valérie F. E. D. Smolders, Kirsten Lodder, Cristina Rodríguez, Olga Tura-Ceide, Joan Albert Barberà, J. Wouter Jukema, Paul H. A. Quax, Marie José Goumans, Kondababu Kurakula
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-03-01
coleção:Cells
Assuntos:
chronic thromboembolic pulmonary hypertension
inflammation
nuclear factor-κB signaling
endothelial dysfunction
Acesso em linha:https://www.mdpi.com/2073-4409/10/4/737
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