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Overexpression of NaV1.6 in the rostral ventrolateral medulla in rats mediates stress-induced hypertension via glutamate regulation

Background The rostral ventrolateral medulla (RVLM) plays a key role in mediating the development of stress-induced hypertension (SIH). Furthermore, enhanced glutamate transport within glutamatergic neurons in the RVLM mediates pressor responses. Data from our previous studies suggest that the volta...

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Principais autores: Lei Tong, Mengyu Xing, Jiaxiang Wu, Shuai Zhang, Dechang Chu, Haili Zhang, Fuxue Chen, Dongshu Du
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis Group 2022-02-01
Serier:Clinical and Experimental Hypertension
Fag:
stress-induced hypertension
rostral ventrolateral medulla
nav1.6
vglut1
gad67
Online adgang:http://dx.doi.org/10.1080/10641963.2021.2007942
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